Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CDA | P32320 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033026 | 0.88 | MAPT (0.53) | MAPTCDALMNAALDH1A1MTOR | |
| SCHEMBL5954124 | 0.88 | MAPT (0.53) | MAPTCDALMNAALDH1A1MTOR | |
| SCHEMBL10243962 | 0.88 | MAPT (0.53) | MAPTCDALMNAALDH1A1MTOR | |
| SCHEMBL14570585 | 0.88 | MAPT (0.53) | MAPTCDALMNAALDH1A1MTOR | |
| SCHEMBL31685424 | 0.72 | ADRB1 (0.52) | LMNATP53HTTDNMT1SMN1; SMN2 | |
| SCHEMBL18237107 | 0.70 | ADORA2A (0.46) | SLC29A1ADORA1 | |
| SCHEMBL23813589 | 0.69 | LMNA (0.79) | MAPTCDALMNAALDH1A1MTOR | |
| SCHEMBL6049698 | 0.69 | LMNA (0.79) | MAPTCDALMNAALDH1A1MTOR | |
| SCHEMBL6049693 | 0.69 | LMNA (0.79) | MAPTCDALMNAALDH1A1MTOR | |
| SCHEMBL15798780 | 0.69 | LMNA (0.79) | MAPTCDALMNAALDH1A1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290533-B2 | β-L-2′-deoxy-nucleosides for the treatment of hepatitis B | NOVARTIS AG (CH) | 2016-03-22 | — | — | US | disclosed |