Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612648 | 0.82 | ADK (0.45) | ADK | |
| SCHEMBL17612673 | 0.82 | ADK (0.65) | ADKCA1CA2HSPA8SMN1; SMN2 | |
| SCHEMBL17612666 | 0.82 | ADK (0.53) | ADK | |
| SCHEMBL17612652 | 0.82 | ADK (0.65) | ADKCA1CA2HSPA8SMN1; SMN2 | |
| SCHEMBL17612669 | 0.82 | ADK (0.65) | ADKCA1CA2HSPA8SMN1; SMN2 | |
| SCHEMBL17612670 | 0.81 | ADK (0.44) | ADK | |
| SCHEMBL17612674 | 0.81 | ADK (0.52) | ADKHSPA8 | |
| SCHEMBL17612675 | 0.81 | ADK (0.41) | ADK | |
| SCHEMBL17612647 | 0.81 | ADK (0.44) | ADK | |
| SCHEMBL12870450 | 0.79 | ADK (0.71) | ADKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289398-B2 | Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith | PTC THERAPEUTICS, INC. (US) | 2016-03-22 | — | — | US | disclosed |