Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 9/20 | 0.53 |
| ▸ | AMD1 | P17707 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612669 | 0.90 | ADK (0.65) | ADKADORA1 | |
| SCHEMBL17612673 | 0.90 | ADK (0.65) | ADKADORA1 | |
| SCHEMBL17612652 | 0.90 | ADK (0.65) | ADKADORA1 | |
| SCHEMBL17612674 | 0.88 | ADK (0.52) | ADKAMD1ADORA1 | |
| SCHEMBL17612653 | 0.82 | ADK (0.44) | ADK | |
| SCHEMBL17612661 | 0.82 | AHCY (0.49) | ADK | |
| SCHEMBL17612662 | 0.81 | FBP1 (0.50) | ADKADORA1 | |
| SCHEMBL17612655 | 0.81 | ADK (0.53) | ADKADORA1 | |
| SCHEMBL17612654 | 0.81 | ADK (0.53) | ADKADORA1 | |
| SCHEMBL4875801 | 0.79 | ADK (0.83) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289398-B2 | Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith | PTC THERAPEUTICS, INC. (US) | 2016-03-22 | — | — | US | disclosed |