SCHEMBL1761289

SCHEMBL1761289

C=CCOC(=O)C(=C)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
TSHR P16473 2/20 0.35
MAPT P10636 2/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
MAPK1 P28482 2/20 0.34
LMNA P02545 1/20 0.34
RAB9A P51151 1/20 0.34
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
PTP4A3 O75365 1/20 0.30
PTP4A1 Q93096 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10524566 0.81 CYP3A4 (0.38) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL27719035 0.79 TSHR (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL9286079 0.79 CYP3A4 (0.37) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL177943 0.77 CYP3A4 (0.48) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL11038017 0.76 CYP3A4 (0.35) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL11038020 0.76 CYP3A4 (0.35) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL5142904 0.76
SCHEMBL2774742 0.76
SCHEMBL1082749 0.76 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL83817 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9650451-B2 Fluorine-containing compounds and their polymers useful for anti-reflection film materials and resist compositions CENTRAL GLASS COMPANY, LIMITED (JP) 2017-05-16 US disclosed
US-9184461-B2 Controlled radical copolymerization of fluorinated monomers by xanthate or trithiocarbonate ARKEMA FRANCE (FR) 2015-11-10 US disclosed
US-20140171584-A1 Fluorine-Containing Compounds and Their Polymers Useful for Anti-Reflection Film Materials and Resist Compositions CENTRAL GLASS COMPANY, LIMITED (JP) 2014-06-19 US disclosed
US-20140154611-A1 CONTROLLED RADICAL COPOLYMERIZATION OF FLUORINATED MONOMERS BY XANTHATE OR TRITHIOCARBONATE ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER (FR) 2014-06-05 US disclosed
US-8691491-B2 Fluorine-containing compounds and their polymers useful for anti-reflection film materials and resist compositions CENTRAL GLASS COMPANY, LIMITED (JP) 2014-04-08 US disclosed
US-20110196121-A1 Fluorine-Containing Compounds and their Polymers Useful for Anti-Reflection Film Materials and Resist Compositions CENTRAL GLASS COMPANY, LIMITED (JP) 2011-08-11 US disclosed
US-7947422-B2 Fluorine-containing compounds and their polymers useful for anti-reflection film materials and resist compositions CENTRAL GLASS COMPANY, LIMITED (JP) 2011-05-24 US disclosed
US-7781602-B2 Fluorinated cyclic compound, polymerizable fluoromonomer, fluoropolymer, resist material comprising the same, and method of forming pattern with the same CENTRAL GLASS COMPANY, LIMITED (JP) 2010-08-24 US disclosed
US-20080194764-A1 Fluorinated Cyclic Compound, Polymerizable Fluoromonomer, Fluoropolymer, Resist Material Comprising the Same, and Method of Forming Pattern with the Same CENTRAL GLASS COMPANY LIMITED (JP) 2008-08-14 US disclosed
US-7232917-B2 Cyclic fluorine compounds, polymerizable fluoromonomers, fluoropolymers, and resist materials containing the fluoropolymers and method for pattern formation CENTRAL GLASS COMPANY, LIMITED (JP) 2007-06-19 US disclosed
US-7105618-B2 Fluorine-containing polymerizable monomers and polymers, anti-reflection film materials and resist compositions using same CENTRAL GLASS COMPANY, LIMITED (JP) 2006-09-12 US disclosed
US-20060194143-A1 Fluorine-containing polymerizable monomers, fluorine-containing polymer compounds, resist compositions using the same, and patterning process CENTRAL GLASS COMPANY, LIMITED (JP) 2006-08-31 US disclosed
US-20060135744-A1 Fluorinated cyclic compound, polymerizable fluoromonomer, fluoropolymer, resist material comprising the same, and method of forming pattern with the same CENTRAL GLASS COMPANY LIMITED (JP) 2006-06-22 US disclosed
US-20060057489-A1 Lactone compounds, lactone-containing monomers, their polymers, resist compositions using same, and processes for forming patterns using same CENTRAL GLASS COMPANY, LIMITED (JP) 2006-03-16 US disclosed
US-6858760-B2 Fluorine-containing cyclic compounds, fluorine-containing polymerizable monomers, fluorine-containing polymers resist compositions and patterning method CENTRAL GLASS COMPANY, LIMITED (JP) 2005-02-22 US disclosed
US-20040225159-A1 Fluorine-containing cyclic compounds, fluorine-containing polymerizable monomers, fluorine-containing polymers resist compositions and patterning method CENTRAL GLASS COMPANY, LTD. (JP) 2004-11-11 US disclosed
US-20040106755-A1 Fluorine containing compounds with unsaturated ether or ester groups CENTRAL GLASS COMPANY, LIMITED (JP) 2004-06-03 US disclosed
US-20030232940-A1 Fluorine-containing polymerizable monomers and polymers, anti-reflection film materials and resist compositions using same CENTRAL GLASS COMPANY, LIMITED (JP) 2003-12-18 US disclosed
EP-0271212-B1 PROCESS FOR PREPARATION OF CARBOXYLIC ACID ESTER CONTAINING FLUORINE Tosoh Corporation (JP) 1992-09-16 EP disclosed
EP-0271212-A2 Process for preparation of carboxylic acid ester containing fluorine Tosoh Corporation (JP) 1988-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135744-A1 Fluorinated cyclic compound, polymerizable fluoromonomer, fluoropolymer, resist material comprising the same, and method of forming pattern with the same PFAS, AFF1, FUBP1 CYP3A4 2773/4885TSHR 3489/4885MAPT 3079/4885
US-20110196121-A1 Fluorine-Containing Compounds and their Polymers Useful for Anti-Reflection Film Materials and Resist Compositions DNMT3B, DNMT3L, AFF1 CYP3A4 4122/4885TSHR 1280/4885MAPT 2854/4885
US-20030232940-A1 Fluorine-containing polymerizable monomers and polymers, anti-reflection film materials and resist compositions using same AFF1, AFF4, AFF2 CYP3A4 3572/4885TSHR 1747/4885MAPT 2141/4885
US-20080194764-A1 Fluorinated Cyclic Compound, Polymerizable Fluoromonomer, Fluoropolymer, Resist Material Comprising the Same, and Method of Forming Pattern with the Same PFAS, AFF1, AFF2 CYP3A4 3028/4885TSHR 3349/4885MAPT 2840/4885
US-20040225159-A1 Fluorine-containing cyclic compounds, fluorine-containing polymerizable monomers, fluorine-containing polymers resist compositions and patterning method AFF1, FPR1, AFF2 CYP3A4 2608/4885TSHR 1278/4885MAPT 3202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.