Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 8/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.33 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | BCR | P11274 | 4/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465091 | 0.85 | GPR142 (0.46) | GPR142ABL1BCRBRAF | |
| SCHEMBL12465242 | 0.79 | GPR142 (0.52) | GPR142ABL1BCRBRAF | |
| SCHEMBL17612960 | 0.77 | DDR2 (0.49) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12465162 | 0.76 | BRAF (0.47) | GPR142ABL1BCRTEKBRAF | |
| SCHEMBL13960551 | 0.74 | KIT (0.33) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL17612891 | 0.74 | BRAF (0.42) | ABL1BCRBRAF | |
| SCHEMBL17612914 | 0.74 | DDR2 (0.49) | DDR2DDR1ABL1BCRKIT | |
| SCHEMBL12465279 | 0.73 | GPR142 (0.44) | GPR142DDR2DDR1ABL1BCR | |
| SCHEMBL12397132 | 0.73 | GPR142 (0.47) | GPR142ABL1BCRBRAF | |
| SCHEMBL12397125 | 0.73 | ABL1 (0.48) | GPR142DDR2DDR1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |