Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 6/20 | 0.40 |
| ▸ | ABL1 | P00519 | 11/20 | 0.38 |
| ▸ | BCR | P11274 | 11/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612990 | 0.93 | BRAF (0.41) | BRAFABL1BCRGPR142 | |
| SCHEMBL12465132 | 0.90 | GPR142 (0.43) | BRAFABL1BCRGPR142 | |
| SCHEMBL12397507 | 0.83 | GPR142 (0.47) | BRAFABL1BCRGPR142 | |
| SCHEMBL12465130 | 0.83 | GPR142 (0.43) | BRAFABL1BCRGPR142 | |
| SCHEMBL17612930 | 0.82 | BRAF (0.39) | BRAFABL1BCRGPR142 | |
| SCHEMBL12465269 | 0.82 | BRAF (0.45) | BRAFABL1BCR | |
| SCHEMBL12465189 | 0.80 | BRAF (0.45) | BRAFABL1BCRGPR142 | |
| SCHEMBL12465135 | 0.79 | ABL1 (0.48) | ABL1BCR | |
| SCHEMBL12465271 | 0.79 | BRAF (0.43) | BRAF | |
| SCHEMBL12465343 | 0.78 | TEK (0.52) | BRAFABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |