Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15046469 | 0.78 | CYP3A4 (0.31) | — | |
| SCHEMBL15046465 | 0.77 | — | — | |
| SCHEMBL15046470 | 0.70 | — | — | |
| SCHEMBL15046460 | 0.70 | HRH4 (0.31) | HRH4 | |
| SCHEMBL17822438 | 0.69 | HRH4 (0.58) | HRH4 | |
| SCHEMBL38665339 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL5145383 | 0.65 | HTR3E (0.46) | HRH4ROCK2ROCK1 | |
| SCHEMBL17613150 | 0.65 | HRH4 (0.33) | HRH4 | |
| SCHEMBL15046455 | 0.65 | — | — | |
| SCHEMBL31582317 | 0.62 | CHRM4 (0.40) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2790660-B1 | CATIONIC TETRAHYDROPYRAZOLOPYRIDINES, DYE COMPOSITION COMPRISING SUCH OXIDATION BASES, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF | ORÉAL L (FR) | 2016-03-23 | — | — | EP | disclosed |