Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | SORD | Q00796 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268018 | 0.85 | CXCR4 (0.40) | CXCR4HRH4HRH3SETDB1MAPK8 | |
| SCHEMBL13230478 | 0.82 | HRH4 (0.47) | CXCR4HRH4IDO1SETDB1MAPT | |
| SCHEMBL17613399 | 0.78 | KDM4E (0.40) | CXCR4SETDB1MAPK8NLRP3 | |
| SCHEMBL15290719 | 0.76 | IDO1 (0.40) | IDO1 | |
| SCHEMBL17613404 | 0.75 | IDO1 (0.39) | IDO1 | |
| SCHEMBL15268009 | 0.71 | HTR1A (0.38) | IDO1 | |
| SCHEMBL15268011 | 0.71 | HTT (0.41) | IDO1MAPK8 | |
| SCHEMBL13330355 | 0.71 | HTR1A (0.38) | IDO1 | |
| SCHEMBL28288902 | 0.71 | CXCR4 (0.64) | CXCR4HRH4HRH3 | |
| SCHEMBL17613400 | 0.70 | TRPV1 (0.39) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367824-B1 | Anti-viral derivatives of pyrimidine | ABBVIE INC (US) | 2016-03-23 | — | — | EP | disclosed |