Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 5/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13171247 | 0.98 | MEN1 (0.59) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL12305127 | 0.95 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL12094240 | 0.88 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL16089528 | 0.80 | MGLL (0.54) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL16095854 | 0.78 | MGLL (0.61) | ALDH1A1SMN1; SMN2MGLLFAAHHPGD | |
| SCHEMBL12021061 | 0.78 | MGLL (0.61) | ALDH1A1SMN1; SMN2MGLLFAAHHPGD | |
| SCHEMBL17742317 | 0.78 | MGLL (0.38) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL11911312 | 0.77 | MGLL (0.59) | ALDH1A1SMN1; SMN2MGLLFAAHHPGD | |
| SCHEMBL29364882 | 0.77 | MGLL (0.59) | ALDH1A1SMN1; SMN2MGLLFAAHHPGD | |
| SCHEMBL27889238 | 0.76 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493609-B2 | N-maleimidyl polymer derivatives | NEKTAR THERAPEUTICS (US) | 2016-11-15 | — | — | US | disclosed |
| US-20160083514-A1 | N-MALEIMIDYL POLYMER DERIVATIVES | NEKTAR THERAPEUTICS | 2016-03-24 | — | — | US | disclosed |