Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 4/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17617926 | 0.92 | P2RY1 (0.49) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16480797 | 0.88 | P2RX3 (0.51) | RNASELP2RX3P2RY1P2RX1P2RX4 | |
| SCHEMBL16480869 | 0.88 | RNASEL (0.64) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16777519 | 0.84 | P2RY1 (0.49) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16777548 | 0.83 | POLA1 (0.53) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16777344 | 0.83 | POLA1 (0.53) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16081063 | 0.83 | P2RY1 (0.51) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16368007 | 0.83 | P2RY2 (0.49) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16480941 | 0.82 | P2RY1 (0.57) | RNASELP2RX3P2RY1P2RX1ENPP1 | |
| SCHEMBL16480885 | 0.82 | NT5E (0.53) | RNASELP2RX3P2RY1P2RX1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083413-A1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083413-A1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | SLC28A2, SLC28A1, SLC29A2 | RNASEL 95/4885P2RX3 1051/4885P2RY1 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.