SCHEMBL17617005

SCHEMBL17617005

COc1c(C)cc(-c2cc3c(s2)C(c2ccc(C(C)(C)C)cc2)(c2ccc(C(C)(C)C)cc2)c2sc(-c4cc(C)c(OC)c(C)c4)cc2C2=C3C(F)(F)C(F)(F)C2(F)F)cc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17617007 0.87 HSD17B1 (0.31)
SCHEMBL17617006 0.86
SCHEMBL10002014 0.85 PRKDC (0.34)
SCHEMBL20147035 0.85
SCHEMBL14838528 0.84 PPARD (0.31)
SCHEMBL17617014 0.82 HSD17B1 (0.32)
SCHEMBL17617021 0.81 PRKDC (0.32)
SCHEMBL17617017 0.81 PRKDC (0.32)
SCHEMBL17617023 0.81 HSD11B1 (0.32)
SCHEMBL20146985 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124524-B2 Diarylethene compounds and uses thereof SOLUTIA CANADA INC. (US) 2021-09-21 US disclosed
US-20190256526-A1 DIARYLETHENE COMPOUNDS AND USES THEREOF SWITCH MATERIALS, INC. (CA) 2019-08-22 US disclosed
US-20160083398-A1 DIARYLETHENE COMPOUNDS AND USES THEREOF SWITCH MATERIALS, INC. (CA) 2016-03-24 US disclosed
US-20160083398-A1 DIARYLETHENE COMPOUNDS AND USES THEREOF SWITCH MATERIALS, INC. (CA) 2016-03-24 US disclosed