Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17617290 | 0.94 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16187403 | 0.93 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19139893 | 0.92 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16187479 | 0.92 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16187432 | 0.91 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19139477 | 0.91 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17617260 | 0.91 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16187480 | 0.91 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16187431 | 0.90 | KMT2A (0.42) | KMT2AMEN1 | |
| SCHEMBL17617259 | 0.90 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-03-24 | — | — | US | disclosed |
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | DDT, DHPS, HPD | KMT2A 1800/4885MEN1 4465/4885SMN1; SMN2 4705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.