SCHEMBL17617872

SCHEMBL17617872

COP(=O)(Cc1ccc2ccc3ccc(CP(=O)(OC)OC)nc3c2n1)OC

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.42
PDE10A Q9Y233 1/20 0.36
PARP1 P09874 1/20 0.36
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
RAB9A P51151 1/20 0.32
CCR5 P51681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17617874 0.92 PGK1 (0.49) CCR1PDE10APARP1PGK1PGK2
SCHEMBL17617873 0.81 PDE10A (0.41) CCR1PDE10APARP1RAB9ACCR5
SCHEMBL9005990 0.79 CYP1A2 (0.46) PDE10A
SCHEMBL17617876 0.76 CCR1 (0.39) CCR1PDE10A
SCHEMBL17617875 0.75 CCR1 (0.38) CCR1PDE10APARP1PGK1PGK2
SCHEMBL2037665 0.68 KLK8 (0.36) PGK1PGK2
SCHEMBL9171676 0.67 CYP1A2 (0.36) RAB9A
SCHEMBL9168465 0.65 ACP3 (0.38)
SCHEMBL9163760 0.65 TSHR (0.42) RAB9A
SCHEMBL15581732 0.65 CCR1 (0.56) CCR1PDE10APARP1RAB9ACCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9548373-B2 Nonvolatile semiconductor memory device KABUSHIKI KAISHA TOSHIBA (JP) 2017-01-17 US disclosed
US-20160087067-A1 NONVOLATILE SEMICONDUCTOR MEMORY DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2016-03-24 US disclosed