SCHEMBL17617876

SCHEMBL17617876

COP(=O)(CCCCCCc1ccc2ccc3ccc(CCCCCCP(=O)(OC)OC)nc3c2n1)OC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.39
PDE10A Q9Y233 1/20 0.38
KCNH2 Q12809 1/20 0.35
DHFR P00374 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17617871 0.93 S1PR3 (0.35) CCR1PDE10AKCNH2
SCHEMBL18380194 0.92 S1PR1 (0.34) CCR1PDE10AKCNH2
SCHEMBL17617873 0.87 PDE10A (0.41) CCR1PDE10ADHFR
SCHEMBL17617875 0.80 CCR1 (0.38) CCR1PDE10A
SCHEMBL17617872 0.76 CCR1 (0.42) CCR1PDE10A
SCHEMBL31026592 0.72 KCNH2 (0.64) CCR1KCNH2
SCHEMBL10511946 0.72 KCNH2 (0.64) CCR1KCNH2
SCHEMBL10531797 0.72 KCNH2 (0.64) CCR1KCNH2
SCHEMBL11515947 0.71 FAAH (0.46)
SCHEMBL8949633 0.70 SIGMAR1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9548373-B2 Nonvolatile semiconductor memory device KABUSHIKI KAISHA TOSHIBA (JP) 2017-01-17 US disclosed
US-20160087067-A1 NONVOLATILE SEMICONDUCTOR MEMORY DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2016-03-24 US disclosed