SCHEMBL17618294

SCHEMBL17618294

CC(C)(C)n1c2ccccc2c2cc(N(c3ccccc3)c3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)ccc21

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13803848 0.92 TSPO (0.37) PDK2
SCHEMBL12560196 0.87 KDM4E (0.40) PDK2
SCHEMBL25563154 0.87 KDM4E (0.40) PDK2
SCHEMBL15745991 0.85 KDM4E (0.36)
SCHEMBL12559385 0.85 KDM4E (0.36)
SCHEMBL13634124 0.85 MAPT (0.45)
SCHEMBL25563549 0.84 KDM4E (0.38) PDK2
SCHEMBL13634133 0.84 MEN1 (0.40) PDK2
SCHEMBL25563620 0.84 KDM4E (0.38) PDK2
SCHEMBL27099745 0.84 PDK2 (0.33) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9548457-B2 Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORIES CO., LTD. (JP) 2017-01-17 US disclosed
US-9548457-B2 Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORIES CO., LTD. (JP) 2017-01-17 US disclosed
US-20160087209-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2016-03-24 US disclosed
US-20160087209-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2016-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160087209-A1 SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE GRK1, PTGER2, PTGER1 PDK2 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.