Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21546369 | 0.84 | MAPT (0.55) | MAPTTP53MCHR1NPC1RAB9A | |
| SCHEMBL17620105 | 0.80 | CA2 (0.59) | MAPTTP53SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17620219 | 0.80 | MAPT (0.51) | MAPTTP53MCHR1NPC1RAB9A | |
| SCHEMBL19404042 | 0.69 | MALT1 (0.42) | MAPTTP53MCHR1SMN1; SMN2KMT2A | |
| SCHEMBL18590675 | 0.69 | CA2 (0.57) | MAPTGAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL2774874 | 0.65 | CNR1 (0.64) | MAPTTP53MCHR1NPC1RAB9A | |
| SCHEMBL25305249 | 0.65 | MAPT (0.65) | MAPTTP53MCHR1NPC1RAB9A | |
| SCHEMBL6890851 | 0.64 | KDM4E (0.68) | MAPTNPC1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL11707941 | 0.64 | CYP2D6 (0.91) | MAPTMCHR1NPC1RAB9ACYP2D6 | |
| SCHEMBL3018104 | 0.64 | MCHR1 (0.77) | MAPTMCHR1NPC1RAB9ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044808-A1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | NEW YORK BLOOD CENTER, INC. (US) | 2016-03-24 | — | — | WO | disclosed |