Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.64 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.56 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.56 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.56 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582082 | 0.94 | TAAR1 (0.65) | CNR1TAAR1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL1728418 | 0.85 | CNR1 (0.59) | CNR1ADAMTS5LMNAPLAAT5PLAAT4 | |
| SCHEMBL2773493 | 0.85 | EPHX2 (0.70) | CNR1TAAR1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL16936556 | 0.84 | CNR1 (0.60) | CNR1TAAR1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL2771801 | 0.83 | MCHR1 (0.49) | CNR1MCHR1TAAR1ADAMTS5MAPT | |
| SCHEMBL23111915 | 0.82 | MCHR1 (0.50) | CNR1MCHR1TAAR1CYP1A2CYP2C19 | |
| SCHEMBL6223646 | 0.81 | MCHR1 (0.77) | CNR1MCHR1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL8163393 | 0.81 | MCHR1 (0.77) | CNR1MCHR1CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL23828908 | 0.81 | ROCK2 (0.62) | MAPTNPC1RAB9ASMN1; SMN2PSEN1 | |
| SCHEMBL6708022 | 0.79 | L3MBTL1 (0.49) | CNR1TAAR1CYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590321-B1 | ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY | SANOFI AVENTIS (FR) | 2010-04-28 | — | — | EP | disclosed |