Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962212 | 0.95 | FAAH (0.54) | FAAH | |
| SCHEMBL2427672 | 0.80 | FAAH (0.45) | FAAH | |
| SCHEMBL3442510 | 0.76 | FAAH (0.61) | FAAHTRPV1 | |
| SCHEMBL13992138 | 0.76 | FAAH (0.66) | FAAH | |
| SCHEMBL3258353 | 0.75 | TRPV1 (0.60) | FAAHTRPV1 | |
| SCHEMBL16585513 | 0.74 | TRPV1 (0.59) | FAAHTRPV1 | |
| SCHEMBL1032935 | 0.74 | FAAH (0.59) | FAAH | |
| SCHEMBL3636693 | 0.74 | FAAH (0.67) | FAAH | |
| SCHEMBL3641485 | 0.74 | FAAH (0.67) | FAAH | |
| SCHEMBL3644234 | 0.74 | FAAH (0.69) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296723-B2 | NAMPT inhibitors | ABBVIE INC. (US) | 2016-03-29 | — | — | US | disclosed |