Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091477 | 0.85 | — | — | |
| SCHEMBL17623004 | 0.85 | MAPK13 (0.32) | — | |
| SCHEMBL16091376 | 0.85 | KDM4E (0.32) | — | |
| SCHEMBL16091493 | 0.82 | — | — | |
| SCHEMBL17623469 | 0.82 | CHEK1 (0.30) | — | |
| SCHEMBL16091227 | 0.81 | TKT (0.32) | — | |
| SCHEMBL16091214 | 0.81 | AURKA (0.34) | — | |
| SCHEMBL17623358 | 0.80 | — | — | |
| SCHEMBL16091292 | 0.78 | — | — | |
| SCHEMBL16091488 | 0.77 | ACACB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |