Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091214 | 0.87 | AURKA (0.34) | — | |
| SCHEMBL17622758 | 0.85 | CYP1A2 (0.33) | — | |
| SCHEMBL17623114 | 0.85 | MAPK13 (0.31) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL16091376 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL17622686 | 0.80 | MAPK13 (0.31) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL16091493 | 0.77 | — | — | |
| SCHEMBL16091227 | 0.77 | TKT (0.32) | — | |
| SCHEMBL17623469 | 0.74 | CHEK1 (0.30) | — | |
| SCHEMBL16091292 | 0.74 | — | — | |
| SCHEMBL17623241 | 0.73 | JAK2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |