Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17623004 | 0.87 | MAPK13 (0.32) | — | |
| SCHEMBL16091493 | 0.76 | — | — | |
| SCHEMBL16091292 | 0.72 | — | — | |
| SCHEMBL17622723 | 0.72 | AURKA (0.43) | AURKA | |
| SCHEMBL17623469 | 0.70 | CHEK1 (0.30) | AURKA | |
| SCHEMBL17622686 | 0.68 | MAPK13 (0.31) | — | |
| SCHEMBL17623456 | 0.68 | PRMT5 (0.33) | — | |
| SCHEMBL17623352 | 0.64 | TP53 (0.41) | AURKA | |
| SCHEMBL17623241 | 0.64 | JAK2 (0.30) | — | |
| SCHEMBL16089516 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144169-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |