Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | CMA1 | P23946 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17622894 | 0.84 | POLB (0.51) | KDM4EALDH1A1USP2LMNAMAPT | |
| SCHEMBL17622884 | 0.79 | EP300 (0.73) | EP300CREBBP | |
| SCHEMBL17623028 | 0.77 | PKM (0.48) | KDM4EALDH1A1LMNAMAPTCYP1A2 | |
| SCHEMBL17622943 | 0.77 | LMNA (0.66) | ALDH1A1LMNAADORA3SMN1; SMN2EP300 | |
| SCHEMBL7202789 | 0.77 | LMNA (0.66) | ALDH1A1LMNAADORA3SMN1; SMN2EP300 | |
| SCHEMBL17622981 | 0.77 | EP300 (0.59) | ALDH1A1LMNAADORA3KMT2ASMN1; SMN2 | |
| SCHEMBL17610653 | 0.75 | LMNA (0.47) | KDM4EALDH1A1LMNAMAPTPOLB | |
| SCHEMBL17623035 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL17622891 | 0.72 | KMT2A (0.52) | ALDH1A1USP2LMNAMAPTHTT | |
| SCHEMBL17622814 | 0.70 | LMNA (0.44) | KDM4EALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044777-A1 | HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-03-24 | — | — | WO | disclosed |