Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344447 | 0.80 | PDPK1 (0.36) | PDPK1ALDH1A1HSD17B10 | |
| SCHEMBL19724521 | 0.79 | APLNR (0.30) | — | |
| SCHEMBL6796490 | 0.76 | PDPK1 (0.45) | PDPK1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL16091312 | 0.72 | LIMK1 (0.36) | EGFR | |
| SCHEMBL17623236 | 0.72 | CNR2 (0.31) | KDM4EALDH1A1 | |
| SCHEMBL12051534 | 0.70 | PDPK1 (0.41) | PDPK1LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL19215165 | 0.70 | — | — | |
| SCHEMBL179602 | 0.67 | LIMK1 (0.38) | PDPK1LMNATP53ALDH1A1HSD17B10 | |
| SCHEMBL179607 | 0.67 | PDPK1 (0.38) | PDPK1TSHRALDH1A1HSD17B10 | |
| SCHEMBL23717803 | 0.67 | PDPK1 (0.38) | PDPK1CYP3A4TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |