Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDXK | O00764 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17623239 | 0.80 | PDPK1 (0.34) | PDPK1HSD17B10ALDH1A1 | |
| SCHEMBL6796490 | 0.79 | PDPK1 (0.45) | PDPK1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL25141404 | 0.78 | PDXK (0.36) | PDXK | |
| SCHEMBL16399428 | 0.74 | PDPK1 (0.38) | PDPK1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL12051534 | 0.73 | PDPK1 (0.41) | PDPK1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL179602 | 0.70 | LIMK1 (0.38) | PDPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL23717803 | 0.70 | PDPK1 (0.38) | PDPK1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL3921763 | 0.70 | ALDH1A1 (0.39) | PDPK1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL179607 | 0.70 | PDPK1 (0.38) | PDPK1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL17623163 | 0.70 | LIMK1 (0.38) | PDXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076975-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |