SCHEMBL17624753

SCHEMBL17624753

O=C(O)C(Cc1ccccc1)NC(=O)C(O)C(O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 10/20 0.67
▸ ACE2 Q9BYF1 6/20 0.60
▸ ACE P12821 5/20 0.60
▸ CPA1 P15085 5/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.56
▸ NAALAD2 Q9Y3Q0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17624791 0.90 MME (0.56) MMEACE2ACECPA1NAALAD2
SCHEMBL14958858 0.89 MME (0.61) MMEACE2ACECPA1NPSR1
SCHEMBL3785458 0.88 MME (0.60) MMEACE2ACECPA1NPSR1
SCHEMBL3785447 0.88 MME (0.60) MMEACE2ACECPA1NPSR1
SCHEMBL12341129 0.88 MME (0.60) MMEACE2ACECPA1NPSR1
SCHEMBL3785450 0.88 MME (0.60) MMEACE2ACECPA1NPSR1
SCHEMBL31390164 0.87 MME (0.63) MMEACE2ACECPA1
SCHEMBL31390141 0.87 MME (0.63) MMEACE2ACECPA1
SCHEMBL11414321 0.86 MME (0.61) MMEACE2ACECPA1NPSR1
SCHEMBL11414316 0.86 MME (0.61) MMEACE2ACECPA1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795678-B2 Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound ADOCIA (FR) 2017-10-24 — — US disclosed
US-20160082106-A1 Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound ADOCIA (FR) 2016-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160082106-A1 Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound IAPP, GPR119, INSR MME 1692/4885ACE2 2043/4885ACE 849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback