Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH4 | P08319 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625063 | 0.86 | CYP2D6 (0.31) | — | |
| SCHEMBL17625044 | 0.83 | — | — | |
| SCHEMBL17624736 | 0.79 | — | — | |
| SCHEMBL9173264 | 0.78 | ADH1B (0.44) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL17624942 | 0.77 | ALDH1A1 (0.30) | TP53 | |
| SCHEMBL17624873 | 0.77 | — | — | |
| SCHEMBL17625027 | 0.73 | DPP4 (0.35) | — | |
| SCHEMBL23519562 | 0.72 | ADH1B (0.50) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL2401995 | 0.72 | ADH1B (0.50) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL7762311 | 0.70 | ADH1B (0.54) | OPRM1ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044585-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |