Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900523 | 0.80 | MAPT (0.60) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL431028 | 0.69 | CDK8 (1.00) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL4902783 | 0.63 | PPARG (0.64) | KDM4EHPGDLIMK1CDC7DBF4 | |
| SCHEMBL18849179 | 0.58 | CDK8 (0.80) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL16838740 | 0.57 | NOTUM (0.46) | NPC1RAB9AMAT2AMEN1KMT2A | |
| SCHEMBL6968638 | 0.57 | KMT2A (0.57) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL19769160 | 0.56 | CDK8 (0.77) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL8401183 | 0.56 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL3094239 | 0.56 | EP300 (0.58) | TDP1MEN1KMT2A | |
| SCHEMBL311158 | 0.56 | KMT2A (0.56) | KDM4EALDH1A1MAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9521850-B2 | Antimicrobial compounds and their use in treating plant disease | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160081341-A1 | ANTIMICROBIAL COMPOUNDS AND THEIR USE IN TREATING PLANT DISEASE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081341-A1 | ANTIMICROBIAL COMPOUNDS AND THEIR USE IN TREATING PLANT DISEASE | SEC23A, SEC13, NAAA | KDM4E 4015/4885ALDH1A1 3754/4885HPGD 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.