Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PDE5A | O76074 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760604 | 1.00 | KDM4E (0.70) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL17760562 | 0.92 | PDE5A (0.69) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL17760548 | 0.92 | PDE5A (0.69) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL16067303 | 0.88 | KDM4E (0.73) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL8316946 | 0.88 | KDM4E (0.73) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL16067300 | 0.88 | KDM4E (0.64) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL687360 | 0.85 | MEN1 (0.74) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL14122016 | 0.85 | PDE5A (0.67) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL14121883 | 0.85 | PDE5A (0.67) | KDM4EMEN1KMT2AALDH1A1CYP2D6 | |
| SCHEMBL14122143 | 0.85 | PDE5A (0.67) | KDM4EMEN1KMT2AALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9521850-B2 | Antimicrobial compounds and their use in treating plant disease | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160081341-A1 | ANTIMICROBIAL COMPOUNDS AND THEIR USE IN TREATING PLANT DISEASE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081341-A1 | ANTIMICROBIAL COMPOUNDS AND THEIR USE IN TREATING PLANT DISEASE | SEC23A, SEC13, NAAA | KDM4E 4015/4885MEN1 3542/4885KMT2A 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.