Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.83 |
| ▸ | MPO | P05164 | 3/20 | 0.78 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.76 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CCNK | O75909 | 1/20 | 0.65 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30776649 | 0.90 | PRMT5 (0.78) | MAPTALDH1A1MPOPRMT5WDR77 | |
| SCHEMBL12486391 | 0.88 | MPO (1.00) | MAPTALDH1A1MPOPRMT5WDR77 | |
| SCHEMBL12485740 | 0.88 | MPO (0.81) | MAPTALDH1A1MPOPRMT5WDR77 | |
| SCHEMBL9379490 | 0.84 | KMT2A (0.69) | MAPTALDH1A1MPOPOLBCYP1A2 | |
| SCHEMBL11116603 | 0.84 | KMT2A (0.69) | MAPTALDH1A1MPOPRMT5WDR77 | |
| SCHEMBL6273988 | 0.84 | MAPT (0.79) | MAPTALDH1A1MPOPRMT5WDR77 | |
| SCHEMBL4984149 | 0.84 | MPO (0.64) | MAPTALDH1A1MPOPRMT5WDR77 | |
| SCHEMBL12486648 | 0.83 | MPO (0.78) | MAPTALDH1A1MPOPOLBCYP1A2 | |
| SCHEMBL12487210 | 0.83 | MPO (0.78) | MAPTALDH1A1MPOPOLBCYP1A2 | |
| SCHEMBL15347348 | 0.83 | MPO (1.00) | MAPTALDH1A1MPOPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9521850-B2 | Antimicrobial compounds and their use in treating plant disease | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160081341-A1 | ANTIMICROBIAL COMPOUNDS AND THEIR USE IN TREATING PLANT DISEASE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081341-A1 | ANTIMICROBIAL COMPOUNDS AND THEIR USE IN TREATING PLANT DISEASE | SEC23A, SEC13, NAAA | MAPT 838/4885ALDH1A1 3754/4885MPO 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.