Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625419 | 0.87 | HSP90AB1 (0.46) | FGFR1SLC22A6POLBHPRT1HSP90AA1 | |
| SCHEMBL17608710 | 0.74 | HSP90AB1 (0.44) | FGFR1SLC22A6POLBHPRT1HSP90AA1 | |
| SCHEMBL17625500 | 0.73 | POLB (0.44) | FGFR1SLC22A6POLBHPRT1HSP90AA1 | |
| SCHEMBL16065919 | 0.72 | POLB (0.64) | POLBHPRT1POLA1POLG | |
| SCHEMBL3304318 | 0.71 | FGFR1 (0.66) | FGFR1SLC22A6NSD3 | |
| SCHEMBL15046049 | 0.71 | P2RY1 (0.53) | FGFR1SLC22A6POLA1POLGP2RY1 | |
| SCHEMBL24383709 | 0.69 | HSP90AB1 (0.51) | POLBHSP90AA1HSP90AB1NSD3CDK1 | |
| SCHEMBL17622515 | 0.69 | HSP90AB1 (0.48) | FGFR1SLC22A6POLBHSP90AA1HSP90AB1 | |
| SCHEMBL30824623 | 0.69 | FGFR1 (0.60) | FGFR1SLC22A6POLBHPRT1HSP90AA1 | |
| SCHEMBL1567494 | 0.69 | FGFR1 (0.60) | FGFR1SLC22A6POLBHPRT1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044281-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-24 | — | — | WO | disclosed |