Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 3/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 2/20 | 0.45 |
| ▸ | PDE1A | P54750 | 2/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304318 | 0.81 | FGFR1 (0.66) | SLC22A6FGFR1ADORA2AADORA1ADCY5 | |
| SCHEMBL15045868 | 0.81 | FGFR1 (0.69) | P2RY1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19242632 | 0.76 | YTHDC1 (0.61) | P2RY1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12179919 | 0.74 | YTHDC1 (0.61) | P2RY1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8467638 | 0.72 | ADORA2A (0.56) | P2RY1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18548917 | 0.72 | YTHDC1 (0.62) | P2RY1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17625477 | 0.71 | FGFR1 (0.34) | P2RY1SLC22A6FGFR1POLA1POLG | |
| SCHEMBL17625419 | 0.70 | HSP90AB1 (0.46) | SLC22A6FGFR1POLA1POLG | |
| SCHEMBL13234957 | 0.69 | P2RY1 (0.61) | P2RY1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15257680 | 0.69 | FGFR1 (0.65) | P2RY1SLC22A6FGFR1ABCB11POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090420-A2 | FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |