Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | NSD3 | Q9BZ95 | 6/20 | 0.54 |
| ▸ | NSD2 | O96028 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644453 | 0.85 | SLC22A6 (0.63) | FGFR1SLC22A6ADORA2AADORA1ADCY5 | |
| Adefovir SCHEMBL1262818 | 0.83 | FGFR1 (0.91) | FGFR1SLC22A6ADORA2AADORA1ADCY5 | |
| SCHEMBL2023978 | 0.82 | FGFR1 (0.70) | FGFR1SLC22A6ADORA2AADORA1ADCY5 | |
| SCHEMBL15046049 | 0.81 | P2RY1 (0.53) | FGFR1SLC22A6ADORA2AADORA1ADCY5 | |
| SCHEMBL18902347 | 0.80 | FGFR1 (0.55) | FGFR1SLC22A6ADORA2ANSD3NSD2 | |
| SCHEMBL1920120 | 0.80 | FGFR1 (0.67) | FGFR1SLC22A6ADORA2AADORA1ADCY5 | |
| SCHEMBL4364344 | 0.80 | ADORA2A (0.70) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL382916 | 0.80 | FGFR1 (0.66) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| Adefovir SCHEMBL49373 | 0.80 | FGFR1 (1.00) | FGFR1SLC22A6ADORA2AADORA1ADCY5 | |
| Adefovir SCHEMBL29365535 | 0.80 | FGFR1 (1.00) | FGFR1SLC22A6ADORA2AADORA1ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048956-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-23 | — | — | WO | disclosed |
| US-8884011-B2 | Nucleotide analogues as precursor molecules for antivirals | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2014-11-11 | — | — | US | disclosed |
| US-8884011-B2 | Nucleotide analogues as precursor molecules for antivirals | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2014-11-11 | — | — | US | disclosed |
| US-8884011-B2 | Nucleotide analogues as precursor molecules for antivirals | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2014-11-11 | — | — | US | disclosed |
| WO-2014143643-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-1753762-B1 | LEWIS ACID MEDIATED SYNTHESIS OF CYCLIC ESTERS | METABASIS THERAPEUTICS INC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | disclosed |
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | disclosed |
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | disclosed |
| EP-2086990-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | Centre National De La Recherche Scientifique-CNRS (FR) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008056264-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008056264-A2 | NOVEL NUCLEOTIDE ANALOGUES AS PERCURSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | NUDT1, P2RY1, HPRT1 | FGFR1 3108/4885SLC22A6 988/4885ADORA2A 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.