Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GFER | P55789 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544714 | 0.85 | MAPT (0.43) | MAPK1MAPTGFERALDH1A1KMT2A | |
| SCHEMBL24421702 | 0.84 | MAPK1 (0.40) | MAPK1MAPTGFERALDH1A1KDM4E | |
| SCHEMBL14445331 | 0.83 | MAPK1 (0.53) | MAPK1MAPTGAASLC18A3SMN1; SMN2 | |
| SCHEMBL20884848 | 0.78 | KDM4E (0.52) | MAPK1MAPTGFERALDH1A1KDM4E | |
| SCHEMBL189064 | 0.78 | KDM4E (0.52) | MAPK1MAPTGFERALDH1A1KDM4E | |
| SCHEMBL188063 | 0.78 | KDM4E (0.52) | MAPK1MAPTGFERALDH1A1KDM4E | |
| SCHEMBL17265649 | 0.77 | MAPT (0.42) | MAPK1MAPTGFERALDH1A1KDM4E | |
| SCHEMBL27479144 | 0.74 | SLC18A3 (0.47) | MAPK1MAPTGFERALDH1A1KDM4E | |
| SCHEMBL16569969 | 0.74 | GFER (0.38) | MAPK1GFERALDH1A1GAAHTT | |
| SCHEMBL16569968 | 0.74 | GFER (0.38) | MAPK1GFERALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999699-A1 | PURINE DIONES AS WNT PATHWAY MODULATORS | Agency For Science, Technology And Research (SG) | 2016-03-30 | — | — | EP | disclosed |