Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15175206 | 0.80 | NR1H3 (0.40) | KMT2AMEN1NR1H2NR1H3ALPL | |
| SCHEMBL3582476 | 0.79 | SCN2A (0.42) | KMT2AMEN1ALPLALDH1A1CASP3 | |
| SCHEMBL3583148 | 0.76 | SCN2A (0.47) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL27510936 | 0.72 | MEN1 (0.49) | KMT2AMEN1NR1H2NR1H3ALPL | |
| SCHEMBL16473693 | 0.71 | ALDH1A1 (0.42) | KMT2AMEN1ALPLALDH1A1CASP3 | |
| SCHEMBL5341631 | 0.70 | POLB (0.49) | KMT2AMEN1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL26351127 | 0.70 | CYP3A4 (0.34) | ALPLALDH1A1CASP3HTT | |
| SCHEMBL23860829 | 0.69 | MEN1 (0.45) | KMT2AMEN1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL23861037 | 0.68 | MEN1 (0.41) | KMT2AMEN1NR1H3ALDH1A1POLB | |
| SCHEMBL17610274 | 0.67 | ALDH1A1 (0.47) | NR1H2NR1H3ALPLALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |
| US-20160106102-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| US-20160106102-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| EP-2999338-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160106102-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, ACHE, NISCH | KMT2A 831/4885MEN1 2294/4885NR1H2 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.