Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 4/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | PDE6A | P16499 | 1/20 | 0.45 |
| ▸ | PDE6G | P18545 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | PDE6B | P35913 | 1/20 | 0.45 |
| ▸ | PDE6C | P51160 | 1/20 | 0.45 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17637923 | 0.88 | POLB (0.66) | POLBGAAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL3843205 | 0.78 | KMT2A (0.52) | POLBGAAKMT2AALDH1A1PDE5A | |
| SCHEMBL17628500 | 0.75 | POLB (0.57) | POLBGAAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL17628509 | 0.73 | POLB (0.54) | POLBGAAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19754262 | 0.71 | GAA (0.67) | POLBGAAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL17628502 | 0.71 | NR1H2 (0.48) | POLBGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL24000166 | 0.70 | ALDH1A1 (0.65) | GAAKMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL10015955 | 0.69 | MAOB (0.47) | POLBALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20551734 | 0.68 | ALDH1A1 (0.40) | POLBGAAKMT2AALDH1A1PDE5A | |
| SCHEMBL16858284 | 0.68 | CYP1A2 (0.38) | POLBGAAKMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004065-B1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-10-18 | — | — | EP | disclosed |
| US-9732042-B2 | Method for producing pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-9732042-B2 | Method for producing pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-9732042-B2 | Method for producing pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| EP-3004065-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-31 | — | — | US | disclosed |
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-31 | — | — | US | disclosed |
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-31 | — | — | US | disclosed |
| CN-105228987-A | For the preparation of the method for pyridazine compound | SUMITOMO CHEMICAL CO | 2016-01-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | PLP2, PNPO, CBR3 | POLB 561/4885GAA 1200/4885KMT2A 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.