Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | PDE6A | P16499 | 1/20 | 0.40 |
| ▸ | PDE6G | P18545 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | PDE6B | P35913 | 1/20 | 0.40 |
| ▸ | PDE6C | P51160 | 1/20 | 0.40 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484646 | 0.80 | MAPT (0.44) | KMT2AMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL17628501 | 0.78 | POLB (0.56) | KMT2AMEN1ALDH1A1POLBPDE5A | |
| SCHEMBL8901048 | 0.77 | POLB (0.47) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL469888 | 0.76 | PDE5A (0.45) | KMT2AMEN1ALDH1A1POLBPDE5A | |
| SCHEMBL30388561 | 0.74 | HPD (0.36) | KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27992351 | 0.74 | PDE5A (0.43) | KMT2AMEN1ALDH1A1POLBPDE5A | |
| SCHEMBL20551734 | 0.73 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1POLBPDE5A | |
| SCHEMBL8902547 | 0.73 | SMN1; SMN2 (0.46) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL8903051 | 0.71 | LMNA (0.43) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL22031792 | 0.71 | CASR (0.40) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |