Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740512 | 0.83 | DNMT1 (0.47) | DNMT1TYMPMEN1ALDH1A1MAPT | |
| SCHEMBL27844249 | 0.83 | CA1 (0.59) | DNMT1MEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL3909203 | 0.82 | CA1 (0.52) | DNMT1TYMPMEN1KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL28180680 | 0.81 | CTRB1 (0.49) | DNMT1TYMPMEN1ALDH1A1MAPT | |
| SCHEMBL7332420 | 0.77 | CA1 (0.42) | DNMT1MAPTCA1CA2CA9 | |
| SCHEMBL29410608 | 0.75 | DNMT1 (0.59) | DNMT1TYMPMEN1ALDH1A1MAPT | |
| SCHEMBL57524 | 0.75 | CA1 (0.63) | MEN1ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL29787010 | 0.75 | DNMT1 (0.59) | DNMT1TYMPMEN1ALDH1A1MAPT | |
| SCHEMBL31605318 | 0.75 | CA1 (0.63) | MEN1ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL196007 | 0.75 | DNMT1 (0.59) | DNMT1TYMPMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004065-B1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-10-18 | — | — | EP | disclosed |
| US-9732042-B2 | Method for producing pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| EP-3004065-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-31 | — | — | US | disclosed |
| CN-105228987-A | For the preparation of the method for pyridazine compound | SUMITOMO CHEMICAL CO | 2016-01-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | PLP2, PNPO, CBR3 | DNMT1 346/4885TYMP 394/4885MEN1 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.