SCHEMBL27844249

SCHEMBL27844249

NS(=O)(=O)c1ccc2ccccc2c1-c1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.59
CA9 Q16790 7/20 0.59
CA2 P00918 6/20 0.59
CA12 O43570 6/20 0.53
DNMT1 P26358 1/20 0.47
LDHA P00338 1/20 0.44
STAT3 P40763 1/20 0.44
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NSD2 O96028 1/20 0.41
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
CDK2 P24941 1/20 0.41
DHFR P00374 1/20 0.41
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29786464 0.87 CA1 (0.64) CA1CA9CA2CA12DNMT1
SCHEMBL29740512 0.83 DNMT1 (0.47) CA1CA9CA2CA12DNMT1
SCHEMBL17628504 0.83 DNMT1 (0.47) CA1CA9CA2CA12DNMT1
SCHEMBL11528605 0.80 CA1 (0.71) CA1CA9CA2CA12LDHA
SCHEMBL3620124 0.76 CA2 (0.44) CA1CA9CA2CA12ALDH1A1
SCHEMBL31265318 0.76 CA1 (0.54) CA1CA9CA2CA12LDHA
SCHEMBL29529240 0.75 CA2 (1.00) CA1CA9CA2CA12LDHA
SCHEMBL28464 0.75 CA2 (1.00) CA1CA9CA2CA12LDHA
SCHEMBL3145617 0.74 CA2 (0.74) CA1CA9CA2CA12LDHA
SCHEMBL3922877 0.74 CA1 (0.62) CA1CA9CA2CA12LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751321-A Dinaphthalene sulfonamide derivative and application thereof 中国人民解放军海军军医大学 2025-04-04 CN claimed
CN-102241823-B Binaphthylamine derivative hybrid mesoporous silica gel chiral stationary phase UNIV CHINA PHARMA 2012-10-10 CN disclosed
CN-102241823-A Binaphthylamine derivative hybrid mesoporous silica gel chiral stationary phase UNIV CHINA PHARMA 2011-11-16 CN disclosed