Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL1156616 | 0.93 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 | |
| Fumaric Acid SCHEMBL1156611 | 0.93 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 | |
| SCHEMBL1580961 | 0.89 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 | |
| SCHEMBL1580398 | 0.87 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 | |
| SCHEMBL1580633 | 0.85 | HTR6 (0.40) | KMT2AMAPTPOLBTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL1156896 | 0.84 | HTR6 (0.40) | KMT2AMAPTPOLBTSHRALDH1A1 | |
| Fumaric Acid SCHEMBL1278635 | 0.82 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 | |
| Fumaric Acid SCHEMBL1278638 | 0.82 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 | |
| Fumaric Acid SCHEMBL1278946 | 0.81 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 | |
| Fumaric Acid SCHEMBL1278943 | 0.81 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9186411-B2 | Pharmaceutical composition | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20130261156-A1 | PHARMACEUTICAL COMPOSITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-10-03 | — | — | US | disclosed |
| EP-2564833-A1 | Photostabilized pharmaceutical composition | Takeda Pharmaceutical Company Limited (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20110124687-A1 | PHARMACEUTICAL COMPOSITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124687-A1 | PHARMACEUTICAL COMPOSITION | CYP2C19, MLST8, CYP3A43 | CHRNB2 4514/4885CHRNB4 4698/4885CHRNA3 4204/4885 |
| US-20130261156-A1 | PHARMACEUTICAL COMPOSITION | CYP2C19, MLST8, CYP3A43 | CHRNB2 4514/4885CHRNB4 4698/4885CHRNA3 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.