Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629665 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL214978 | 0.80 | — | — | |
| Nitrogen SCHEMBL27898260 | 0.80 | ALDH1A1 (0.55) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL10901590 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL6115 | 0.79 | — | — | |
| SCHEMBL17449766 | 0.79 | — | — | |
| SCHEMBL1866106 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL11747000 | 0.78 | ALDH1A1 (0.48) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL5902744 | 0.78 | ALDH1A1 (0.52) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL3841890 | 0.78 | GAA (0.48) | ALDH1A1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016045125-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2016-03-31 | — | — | WO | disclosed |