Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 11/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1156568 | 0.99 | PRMT6 (0.44) | PRMT6HTR6FBP1MEN1ALDH1A1 | |
| SCHEMBL1763110 | 0.88 | PRMT6 (0.45) | PRMT6ALDH1A1MET | |
| SCHEMBL1156256 | 0.88 | PRMT6 (0.46) | PRMT6HTR6CYP3A4 | |
| Hydrochloric Acid SCHEMBL1156643 | 0.88 | PRMT6 (0.44) | PRMT6ALDH1A1MET | |
| Hydrochloric Acid SCHEMBL1156593 | 0.87 | PRMT6 (0.45) | PRMT6HTR6CYP3A4 | |
| SCHEMBL1580310 | 0.86 | HTR6 (0.42) | HTR6FBP1MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1156956 | 0.85 | HTR6 (0.42) | HTR6FBP1MEN1ALDH1A1KMT2A | |
| SCHEMBL1580794 | 0.83 | HTR6 (0.41) | HTR6FBP1MEN1ALDH1A1KMT2A | |
| SCHEMBL1156124 | 0.82 | PRMT6 (0.41) | PRMT6ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1156894 | 0.82 | HTR6 (0.40) | HTR6FBP1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9186411-B2 | Pharmaceutical composition | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20130261156-A1 | PHARMACEUTICAL COMPOSITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-10-03 | — | — | US | disclosed |
| EP-2564833-A1 | Photostabilized pharmaceutical composition | Takeda Pharmaceutical Company Limited (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20110124687-A1 | PHARMACEUTICAL COMPOSITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124687-A1 | PHARMACEUTICAL COMPOSITION | CYP2C19, MLST8, CYP3A43 | PRMT6 4087/4885HTR6 1727/4885FBP1 3626/4885 |
| US-20130261156-A1 | PHARMACEUTICAL COMPOSITION | CYP2C19, MLST8, CYP3A43 | PRMT6 4087/4885HTR6 1727/4885FBP1 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.