Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784673 | 0.80 | ENPP2 (0.43) | ALDH1A1NOTUMHTTTSHRKDM4E | |
| SCHEMBL180853 | 0.77 | ALDH1A1 (0.56) | ALDH1A1ALOX15HTTLMNAPOLB | |
| SCHEMBL29365220 | 0.77 | ALDH1A1 (0.56) | ALDH1A1ALOX15HTTLMNAPOLB | |
| SCHEMBL4851536 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ALOX15NOTUMHTTLMNA | |
| SCHEMBL1662301 | 0.76 | ALDH1A1 (0.52) | ALDH1A1ALOX15NOTUMHTTXDH | |
| SCHEMBL27869030 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ALOX15NOTUMHTTLMNA | |
| SCHEMBL6913178 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ALOX15HTTLMNAPOLB | |
| SCHEMBL6913805 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ALOX15HTTLMNAPOLB | |
| Hydrochloric Acid SCHEMBL8901291 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ALOX15HTTLMNAPOLB | |
| SCHEMBL6918558 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ALOX15HTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046782-A1 | IMIDAZOLE BIARYL COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-03-31 | — | — | WO | disclosed |