Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631911 | 0.83 | UCHL1 (0.45) | CDK9UCHL1CHRM4 | |
| SCHEMBL17632036 | 0.80 | USP30 (0.50) | USP30UCHL1 | |
| SCHEMBL17632525 | 0.78 | CHEK1 (0.41) | USP30CDK9UCHL1 | |
| SCHEMBL17631689 | 0.78 | SMN1; SMN2 (0.35) | USP30CDK9 | |
| SCHEMBL17631780 | 0.77 | USP30 (0.39) | USP30CDK9UCHL1 | |
| SCHEMBL17631923 | 0.77 | UCHL1 (0.50) | USP30UCHL1RIPK1 | |
| SCHEMBL17632937 | 0.77 | CHEK1 (0.37) | USP30CDK9UCHL1CHRM4 | |
| SCHEMBL17631847 | 0.77 | USP30 (0.37) | USP30CDK9UCHL1 | |
| SCHEMBL17631604 | 0.75 | DYRK1B (0.44) | USP30UCHL1 | |
| SCHEMBL17632604 | 0.75 | UCHL1 (0.43) | USP30UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |