Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.38 |
| ▸ | BRD4 | O60885 | 11/20 | 0.35 |
| ▸ | BRD2 | P25440 | 6/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 5/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632216 | 0.79 | BRD4 (0.41) | USP30BRD4BRD2BRD3UCHL1 | |
| SCHEMBL17631653 | 0.77 | MAPK14 (0.35) | USP30 | |
| SCHEMBL17632567 | 0.75 | BRD4 (0.47) | USP30BRD4BRD2BRD3UCHL1 | |
| SCHEMBL17632023 | 0.75 | USP30 (0.42) | USP30BRD4BRD2BRD3UCHL1 | |
| SCHEMBL17632015 | 0.73 | USP30 (0.38) | USP30BRD4BRD2BRD3UCHL1 | |
| SCHEMBL21845521 | 0.71 | BRD4 (0.39) | BRD4BRD2BRD3CREBBP | |
| SCHEMBL17631968 | 0.70 | USP30 (0.36) | USP30BRD4BRD2BRD3CREBBP | |
| SCHEMBL17631794 | 0.69 | USP30 (0.35) | USP30BRD4BRD2BRD3 | |
| SCHEMBL17631914 | 0.68 | USP30 (0.61) | USP30UCHL1 | |
| SCHEMBL17632188 | 0.68 | CYP1A2 (0.38) | USP30BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |