Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 5/20 | 0.31 |
| ▸ | BRD2 | P25440 | 3/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632023 | 0.84 | USP30 (0.42) | USP30CYP1A2ALDH1A1CYP2C19CLK4 | |
| SCHEMBL17632567 | 0.84 | BRD4 (0.47) | USP30CYP1A2ALDH1A1CYP2C19CLK4 | |
| SCHEMBL17631794 | 0.84 | USP30 (0.35) | USP30CYP1A2ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL17632188 | 0.84 | CYP1A2 (0.38) | USP30CYP1A2ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL17632015 | 0.77 | USP30 (0.38) | USP30CYP1A2ALDH1A1CYP2C19CLK4 | |
| SCHEMBL17632490 | 0.77 | MAPT (0.43) | ALDH1A1LMNA | |
| SCHEMBL17632621 | 0.76 | ALDH1A1 (0.47) | USP30CYP1A2ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL17631887 | 0.73 | USP30 (0.44) | USP30BRD4 | |
| SCHEMBL17632164 | 0.73 | IKBKB (0.33) | USP30ALDH1A1 | |
| SCHEMBL17632035 | 0.73 | ABL1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |