Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NRAS | P01111 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 6/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632023 | 0.85 | USP30 (0.42) | CYP1A2ALDH1A1CYP2C19USP30CLK4 | |
| SCHEMBL17632567 | 0.85 | BRD4 (0.47) | CYP1A2ALDH1A1CYP2C19USP30CLK4 | |
| SCHEMBL17631968 | 0.84 | USP30 (0.36) | CYP1A2ALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL17632015 | 0.83 | USP30 (0.38) | CYP1A2ALDH1A1CYP2C19USP30CLK4 | |
| SCHEMBL17631794 | 0.80 | USP30 (0.35) | CYP1A2ALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL17632490 | 0.78 | MAPT (0.43) | ALDH1A1CYP2D6LMNAMEN1KMT2A | |
| SCHEMBL17632621 | 0.78 | ALDH1A1 (0.47) | CYP1A2ALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL17631887 | 0.76 | USP30 (0.44) | USP30ABL1BRD4 | |
| SCHEMBL17632035 | 0.74 | ABL1 (0.45) | ABL1 | |
| SCHEMBL17632611 | 0.73 | RAB9A (0.37) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |