Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 10/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631830 | 0.91 | USP30 (0.40) | USP30CHEK1UCHL1 | |
| SCHEMBL17632036 | 0.91 | USP30 (0.50) | USP30CHEK1UCHL1KCNH2 | |
| SCHEMBL17632483 | 0.90 | USP30 (0.42) | USP30CHEK1UCHL1AAK1KCNH2 | |
| SCHEMBL17632150 | 0.89 | USP30 (0.43) | USP30CHEK1UCHL1 | |
| SCHEMBL17632442 | 0.89 | CHEK1 (0.44) | USP30CHEK1UCHL1 | |
| SCHEMBL17632503 | 0.89 | USP30 (0.42) | USP30CHEK1UCHL1AAK1KCNH2 | |
| SCHEMBL17631539 | 0.88 | USP30 (0.42) | USP30CHEK1UCHL1 | |
| SCHEMBL17631685 | 0.86 | DYRK1B (0.44) | USP30CHEK1UCHL1 | |
| SCHEMBL17631604 | 0.86 | DYRK1B (0.44) | USP30CHEK1UCHL1 | |
| SCHEMBL17632491 | 0.86 | CHEK1 (0.42) | USP30CHEK1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |