SCHEMBL1763245

SCHEMBL1763245

N=P(O)(O)OP(=O)(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3984305 0.84 FDPS (0.50)
SCHEMBL2351336 0.84 FDPS (0.50)
SCHEMBL2346609 0.82 FDPS (0.47)
Pyrophosphoric Acid SCHEMBL2420398 0.81 FDPS (0.91)
SCHEMBL8533159 0.80
Pyrophosphoric Acid SCHEMBL3654 0.76
Pyrophosphoric Acid SCHEMBL292348 0.76 FDPS (1.00)
Pyrophosphoric Acid SCHEMBL8851914 0.76 FDPS (1.00)
Pyrophosphoric Acid SCHEMBL29634664 0.76
Pyrophosphoric Acid SCHEMBL28033561 0.74 FDPS (0.77)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233518-A1 CROSSING THE BLOOD BRAIN BARRIER TO TREAT DISEASES OF THE BRAIN HARBOUR ANTIBODIES BV (NL) 2025-11-13 WO claimed
US-20240277872-A1 MODIFIED MRNA, MODIFIED NON-CODING RNA, AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2024-08-22 US claimed
EP-4337331-A1 MODIFIED MRNA, MODIFIED NON-CODING RNA, AND USES THEREOF The Broad Institute Inc. (US) 2024-03-20 EP claimed
US-20230406870-A1 PROCESS FOR PREPARING DIMERIC PHOSPHAZENE DERIVED BRØNSTED ACIDS STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2023-12-21 US claimed
EP-4200308-A1 PROCESS FOR PREPARING DIMERIC PHOSPHAZENE DERIVED BRØNSTED ACIDS Studiengesellschaft Kohle gGmbH (DE) 2023-06-28 EP claimed
CN-116348435-A Process for preparing dimeric phosphazene-derived bronsted acids 科勒研究非盈利有限责任公司 2023-06-27 CN claimed
WO-2022241045-A1 MODIFIED MRNA, MODIFIED NON-CODING RNA, AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2022-11-17 WO claimed
WO-2022073803-A1 PROCESS FOR PREPARING DIMERIC PHOSPHAZENE DERIVED BRØNSTED ACIDS STUDIENGESELLSCHAFT KOHLE MBH (DE) 2022-04-14 WO claimed
US-20210008104-A1 COMPOSITIONS AND METHODS FOR INHIBITING HIV-1 REVERSE TRANSCRIPTASE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2021-01-14 US claimed
EP-3664811-A2 COMPOSITIONS AND METHODS FOR INHIBITING HIV-1 REVERSE TRANSCRIPTASE The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) 2020-06-17 EP claimed
EP-0470965-A1 PREPARATION OF RHENIUM PHOSPHONATE THERAPEUTIC AGENTS. MALLINCKRODT INC (US) 1992-02-19 EP claimed
WO-1992000758-A1 METHOD OF PREPARING A RADIOACTIVE RHENIUM COMPLEX SOLUTION MALLINCKRODT MEDICAL, INC. (US) 1992-01-23 WO claimed
WO-1992000759-A2 STABILIZED THERAPEUTIC RADIOPHARMACEUTICAL COMPLEXES MALLINCKRODT MEDICAL, INC. (US) 1992-01-23 WO claimed
US-5021235-A Preparation of rhenium phosphonate therapeutic agents for bone cancer without purification MALLINCKRODT, INC. (US) 1991-06-04 US claimed
EP-0250966-B1 PROCEDURE FOR ISOLATING AND PURIFYING RADIOACTIVE LIGATED RHENIUM PHARMACEUTICALS AND USE THEREOF AND KIT UNIVERSITY OF CINCINNATI (US) 1991-02-06 EP claimed
WO-1990013530-A1 PREPARATION OF RHENIUM PHOSPHONATE THERAPEUTIC AGENTS MALLINCKRODT, INC. (US) 1990-11-15 WO claimed
US-4935222-A STERILE, PYROGEN-FREE RADIOACTIVE RHENIUM COMPLEX FORMED BY REDUCTION OF PERRHENATE, BONDING TO LIGAND, SEPARATION ON COLUMN UNIVERSITY OF CINCINNATI (US) 1990-06-19 US claimed
EP-0250966-A1 Procedure for isolating and purifying radioactive ligated rhenium pharmaceuticals and use thereof and kit UNIVERSITY OF CINCINNATI (US) 1988-01-07 EP claimed
EP-0043630-B1 IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS GIST-BROCADES N.V. (NL) 1986-01-08 EP claimed
EP-0043630-A2 Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds GIST-BROCADES N.V. (NL) 1982-01-13 EP claimed