Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.32 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.32 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | INPP5B | P32019 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ITPR3 | Q14573 | 3/20 | 0.30 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.30 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL933099 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL8720302 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL145674 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL4346392 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL468667 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL1985595 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL3788496 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL9522730 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL2325329 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 | |
| Pyrophosphoric Acid SCHEMBL2420398 | 0.92 | FDPS (0.91) | FDPSBLMTDP1CA4BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892006-B | A kind of phosphate doped ceramics coating material and preparation method thereof | 黑龙江省科学院高技术研究院 | 2017-12-19 | — | — | CN | claimed |
| CN-104892006-A | Phosphate-doped ceramic coating material and preparation method thereof | INST OF ADVANCED TECHNOLOGY OF HEILONGJIANG ACADEMY OF SCIENCES | 2015-09-09 | — | — | CN | claimed |
| CN-104892006-B | A kind of phosphate doped ceramics coating material and preparation method thereof | 黑龙江省科学院高技术研究院 | 2017-12-19 | — | — | CN | disclosed |
| CN-104892006-B | A kind of phosphate doped ceramics coating material and preparation method thereof | 黑龙江省科学院高技术研究院 | 2017-12-19 | — | — | CN | disclosed |
| CN-104892006-A | Phosphate-doped ceramic coating material and preparation method thereof | INST OF ADVANCED TECHNOLOGY OF HEILONGJIANG ACADEMY OF SCIENCES | 2015-09-09 | — | — | CN | disclosed |