Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 7/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923559 | 0.88 | SYK (0.46) | SYKRORCNAMPTEGLN2MAP4K4 | |
| SCHEMBL14923665 | 0.85 | SYK (0.47) | SYKRORCNAMPTEGLN2MAP4K4 | |
| SCHEMBL14928237 | 0.83 | SYK (0.43) | SYKRORCNAMPTEGLN2AR | |
| SCHEMBL17633200 | 0.82 | SYK (0.43) | SYKRORCNAMPTEGLN2MAP4K4 | |
| SCHEMBL14923668 | 0.82 | SYK (0.42) | SYKRORCNAMPTARCYP17A1 | |
| SCHEMBL29813612 | 0.82 | SYK (0.45) | SYKRORCNAMPTEGLN2MAP4K4 | |
| SCHEMBL15081332 | 0.82 | SYK (0.45) | SYKRORCNAMPTEGLN2MAP4K4 | |
| SCHEMBL2015768 | 0.81 | SYK (0.44) | SYKRORCNAMPTEGLN2MAP4K4 | |
| SCHEMBL29178680 | 0.81 | SYK (0.44) | SYKRORCNAMPTEGLN2MAP4K4 | |
| SCHEMBL31554405 | 0.81 | ALDH1A1 (0.46) | SYKRORCNAMPTMAP4K4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197872-B1 | (2H)-2-OXOPYRIDINES AS FAKTOR XIA-INHIBITORS FOR TREATING THROMBOTIC DISEASES | Bayer Pharma AG (DE) | 2019-01-30 | — | — | EP | disclosed |
| EP-3197872-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046166-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-03-31 | — | — | WO | disclosed |